Ying Yin#, Nixin Tian#, Zhiqin Deng#, Jiaojiao Wang, Lei Kuang, Yuanyang Tang, Siqing Zhu, Zhufeng Dong, Zheng Wang, Xinxia Wu, Mengwei Han, Xiaoye Hu, Yongbing Deng, Tieying Yin*, and Yazhou Wang*，Targeted Microglial Membrane-Coated MicroRNA Nanosponge Mediates Inhibition of Glioblastoma，ACS Nano, 2024, 18, 29089.
Zhiqin Deng#, Huangcan Li#, Shu Chen, Na Wang, Gongyuan Liu, Danjun Liu, Weihui Ou, Feijie Xu, Xiong Wang, Dangyuan Lei, Pui-Chi Lo, Yang Yang Li, Jian Lu, Mengsu Yang, Ming-Liang He*, and Guangyu Zhu*, Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner. Nature Chemistry 2023, 15, 930-939 (同期Nature Chemistry重点报导: Nat. Chem. 2023, 15, 896–898)
Zhiqin Deng and Guangyu Zhu*, Beyond mere DNA damage: recent progress in platinum(IV) anticancer complexes containing multi-Functional axial ligands, Current Opinion in Chemical Biology, 2023, 74, 102303.
Xuefeng Tan#, Zhiqin Deng#, Qingli Wang, Shu Chen, Guangyu Zhu*, and Jianwei Sun*, Enantioselective synthesis of tetraarylmethanes through meta-hydroxyl-directed benzylic substitution, Nature Synthesis 2023, 2, 275.
Gongyuan Liu, Yachao Zhang, Houzong Yao, Zhiqin Deng, Shu Chen, Yue Wang, Wang Peng, Guohan Sun, Man-Kit Tse, Xianfeng Chen, Jianbo Yue, Yung-Kang Peng, Lidai Wang, Guangyu Zhu*, An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy, Science Advances, 2023, 25, eadg5964.
Xinxue Tang, Yuk-Tong Cheng, Junda Shen, Jia-hua Liu, Zhibo Zhang, Zhiqin Deng, Fucong Lyu, Yong Yang, Guangyu Zhu, Zhengtao Xu, Jian Lu*, Yang Yang Li*, Supervariate ceramics: Demineralization via gelation in neutral nontoxic solutions, Advanced Engineering Materials, 2023, 17, 2300430.
Zhiqin Deng,# Houzong Yao,# and Guangyu Zhu*, Chapter00130: Platinum anticancer drugs: Targeting and delivery. “Comprehensive Inorganic Chemistry III”, 2022, Elsevier.
Houzong Yao, Zhigang Wang, Na Wang, Zhiqin Deng, Gongyuan Liu, Jianghong Zhou, Shu Chen, Jiahai Shi, Guangyu Zhu*, Enhancing circulation and tumor accumulation of carboplatin via an erythrocyte-anchored prodrug strategy. Angewandte Chemie International Edition, 2022, e202203838
Bo Li, Jiahua Liu, Fucong Lyu, Zhiqin Deng, Bo Yi, Peng Du, Xi Yao, Guangyu Zhu, Zhengtao Xu, Jian Lu*, Yang Yang Li*, Mineral Hydrogel from Inorganic Salts: Biocompatible Synthesis, All‐in‐One Charge Storage, and Possible Implications in the Origin of Life, Advanced Functional Materials, 2022, 32, 2109302.
Qiaolin Yan, Meng Duan, Cien Chen, Zhiqing Deng, Mandi Wu, Peiyuan Yu, Ming-Liang He, Guangyu Zhu, KN Houk*, Jianwei Sun*, Organocatalytic discrimination of non-directing aryl and heteroaryl groups: enantioselective synthesis of bioactive indole-containing triarylmethanes, Chemical Science, 2022, 13(19), 5767.
Shu Chen, Ka-Yan Ng, Qiyuan Zhou, Houzong Yao, Zhiqin Deng, Man-Kit Tse, Guangyu Zhu*, The influence of different carbonate ligands on the hydrolytic stability and reduction of platinum (IV) prodrugs, Dalton Transactions., 2022, 51(3), 885-897.
Zhiqin Deng, Cai Li, Shu Chen, Qiyuan Zhou, Zoufeng Xu, Zhigang Wang, Houzong Yao, Hajime Hirao, and Guangyu Zhu* An intramolecular photoswitch can significantly promote photoactivation of Pt(IV) prodrugs. Chemical Science 2021, 12, 6536-6542. (封面文章)
Na Wang#, Zhiqin Deng#, Qi Zhu#, Jianxiong Zhao, Kai Xie, Peng Shi, Zhigang Wang, Xianfeng Chen, Feng Wang, and Guangyu Zhu*, An erythrocyte-delivered photoactivatable oxaliplatin nanoprodrug for enhanced antitumor efficacy and immune response, Chemical Science, 2021, 12, 14353-14362. (封面文章)
Zhiqin Deng#, Na Wang#, Fujin Ai#, Zhigang Wang*, and Guangyu Zhu*, Nanomaterial-mediated platinum drug-based combinatorial cancer therapy. VIEW, 2021, 2, 20200030. (封面文章)
Zoufeng Xu, Zhigang Wang, Zhiqin Deng, and Guangyu Zhu* Recent advances in the synthesis and activation of Pt(IV) prodrugs. Coordination Chemistry Reviews, 2021, 442, 213991.
Binbin Zhou, Weihui Ou, Chenghao Zhao, Junda Shen, Guobin Zhang, Xianghu Tang, Zhiqin Deng, Guangyu Zhu, Yang Yang Li*, Jian Lu*, Insertable and reusable SERS sensors for rapid on-site quality control of fish and meat products, Chemical Engineering Journal, 2021, 130733.
Biyun Ren, Bing Chen, Jianxiong Zhao, Yang Guo, Xin Zhang, Xian Chen, Yangyang Du, Zhiqin Deng, Guangyu Zhu, Feng Wang* Synthesis of core–shell ScF3 nanoparticles for thermal enhancement of upconversion. Chemistry of Materials, 2021, 33, 1, 158–163.
Zhiqin Deng, Na Wang, Yingying Liu, Zoufeng Xu, Zhigang Wang, T.-C. Lau, and Guangyu Zhu* A photocaged, water-oxidizing, and nucleolus-targeted Pt(IV) complex with a distinct anticancer mechanism. Journal of the American Chemical Society, 2020, 142, 7803-7812 (封面文章，JACS亮点文章)
Xingguang Li#, Meng Duan#, Zhiqin Deng#, Qianzhen Shao, Min Chen, Guangyu Zhu*, Kendall N. Houk* and Jianwei Sun* Catalytic enantioselective synthesis of chiral tetraarylmethanes. Nature Catalysis, 2020, 12, 1010-1019.
Zhigang Wang#, Zhiqin Deng#, and Guangyu Zhu*, Emerging platinum (IV) prodrugs to combat cisplatin resistance: from isolated cancer cells to tumor microenvironment, Dalton Transactions, 2019, 48(8): 2536-2544. (封面文章).
Yangyang Du, Yunfeng Wang, Zhiqin Deng, Xian Chen, Xueqing Yang, Tianying Sun, Xin Zhang, Guangyu Zhu, Siu Fung Yu, Feng Wang*, Blue-Pumped Deep Ultraviolet Lasing from Lanthanide-Doped Lu6O5F8 Upconversion Nanocrystals, Advanced Optical Materials, 2020, 8, 1900968.
Houzong Yao, Shu Chen, Zhiqin Deng, Man-Kit Tse, Yudai Matsuda, Guangyu Zhu*, BODI-Pt, a Green-Light-Activatable and Carboplatin-Based Platinum (IV) Anticancer Prodrug with Enhanced Activation and Cytotoxicity. Inorganic Chemistry, 2020, 59(16): 11823-11833.
Zhigang Wang, Na Wang, Shun-Cheung Cheng, Kai Xu, Zhiqin Deng, Shu Chen, Zoufeng Xu, Kai Xie, Man-Kit Tse, Peng Shi, Hajime Hirao, Chi-Chiu Ko, Guangyu Zhu*, Phorbiplatin, a highly potent Pt (IV) antitumor prodrug that can be controllably activated by red light, Chem, 2019, 5(12): 3151-3165.
Zoufeng Xu, Cai Li, Qiyuan Zhou, Zhiqin Deng, Zixuan Tong, Man-Kit Tse, Guangyu Zhu*, Synthesis, Cytotoxicity, and Mechanistic Investigation of Platinum (IV) Anticancer Complexes Conjugated with Poly (ADP-ribose) Polymerase Inhibitors, Inorganic Chemistry, 2019, 58(23): 16279-16291.
Zhiqin Deng#, Pan Gao#, Lianling Yu#, Bin Ma, Yuanyuan You, Leung Chan, Chaoming Mei, Tianfeng Chen*, Ruthenium complexes with phenylterpyridine derivatives target cell membrane and trigger death receptors-mediated apoptosis in cancer cells, Biomaterials, 2017, 129: 111-126.
Zhiqin Deng#, Lianling Yu#, Wenqiang Cao, Wenjie Zheng, and Tianfeng Chen*, A selenium-containing ruthenium complex as cancer radiosensitizer, rational design and important role of ROS-mediated signalling, Chemical Communications, 2015, 51 (13): 2637-2640.
Zhiqin Deng, Lianling Yu, Wenqiang Cao, Wenjie Zheng, and Tianfeng Chen*, Rational Design of Ruthenium Complexes Containing 2,6-Bis(benzimidazolyl) pyridine Derivatives with Radiosensitization Activity by Enhancing p53 Activation, ChemMedChem, 2015, 10(6): 991-998. (封面文章)
专利：
[1] Near-infrared light-activatable platinum(IV) prodrugs, preparation thereof and therapeutic use thereof (17/824,174，美国)
[2] 铂(IV)络合物、其制造方法、包含其的组合物及其使用方法 （No. CN 115521341 A）
